Crudden Research Lab




Maekawa, Z. T. Ariki, M. Nambo*, C. M. Crudden*, “Pyridine-catalyzed desulfonative borylation of benzyl sulfones.” Org. & Biomol. Chem., 2019, Advance article.

C. -H. Yim, M. Nambo*, Y. Tahara, C. M. Crudden*, “Copper-Catalyzed Desulfonative Cross-Coupling of Benzhydryl Sulfones with Azoles.” Chem. Lett., 2019, Advanced online publication.

M.R. Narouz, S. Takano, P.A. Lummis, T.I. Levchenko, A. Nazemi, S. Kaappa, S. Malola, S. Yousefalizadeh, L.A. Calhoun, K.G. Stamplecoskie*, H. Häkkinen*, T. Tsukuda* and C.M. Crudden*, “Robust, Highly Luminescent Au13 Superatoms Protected by N-Heterocyclic Carbenes,” 2019, under consideration. Preprint via ChemRxiv.

M. Nambo*, J.C.H. Yim, L.B.O. Freitas, Y. Tahara, Z.T. Ariki, Y. Maekawa, D. Yokogawa, C.M. Crudden* “Modular Synthesis of a-fluorinated Arylmethanes via Desulfonative Cross-Coupling” Nature Communications, 2019, accepted for publication.

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D. -M. Yan, C. M. Crudden*, J. -R. Chen*, W. -J. Xiao*, “A Career In Catalysis: Howard Alper.” ACS Catal., 2019, 9 (7), 6467 – 6483.

O. L. Torres-Rocha, X. Wu, C. Zhu, C. M. Crudden*, M. F. Cunningham*, “Synthesis of Diblock and Triblock Polymers from Cyclooctadiene and Norbornene Via ROMP in Miniemulsion.” Macromolecular Rapid Comm, 2019, 40, 1900087.


M.R. Narouz, P.J. Unsworth, K. Salorinne, S. Takano, R. Tomihara, S. Kaappa, S. Malola, C.-T. Dinh, J.D. Padmos, K. Ayoo, P.J. Garrett, M. Nambo, J.H. Horton, E.H. Sargent, H. Häkkinen*, T. Tsukuda*, C. M. Crudden*, “N-Heterocyclic carbene-functionalized magic number gold nanoclusters.” Nature Chemistry, 2019, 11, 419 – 425.

C.A. Smith, M. Narouz, P.A. Lummis, I. Singh, A. Nazemi, C.-H. Li, C.M. Crudden*, “N-Heterocyclic Carbenes in Materials Chemistry.” Chemical Reviews, 2019, 119 (11), 4986 – 5056.

M. Nambo, Y. Tahara, J.C-H. Yim, C.M. Crudden, “Cu-Catalyzed Desulfonative Amination of Benzhydryl Sulfones,” Chemistry A European Journal, 2019, 25 (8), 1923-1926.

H. Chen, J. Saunders, S. Borijan, X. Wu, C.M. Crudden, D.-X. Xu, H.-P. Loock* “Microresonators: Tetrasulfide‐Functionalized Mesoporous Silica on Nanowire Ring Resonators for Detection of Aqueous Lead, Pb(II)” Advanced Sustainable Systems, 2019, 3, 1800084.

O.L. Torres-Rocha, X. Wu, C.Y. Zhu, C.M. Crudden, M.F. Cunningham*, “Polymerization-Induced Self-Assembly (PISA) of 1,5-Cyclooctadiene Using Ring Opening Metathesis Polymerization” Macromolecular Rapid Communications, 2019, 40, 1800326.


Y. Zeng, T. Zhang, M. Narouz, C.M. Crudden*, P.H. McBreen*, “Generation and Conversion of an N-Heterocyclic Carbene on Pt(111).” Chemical Communications, 2018, 54, 12527-12530.

Z. Li, K. Munro, M.R. Narouz, A. Lau, H. Hao, C.M. Crudden, J.H. Horton “Self-Assembled N-Heterocyclic Carbene-Based Carboxymethylated Dextran Monolayers on Gold as Tunable Platform for Designing Affinity-Capture Biosensor Surfaces.” ACS Applied Materials & Interfaces, 2018, 10, (21), 17560-17570.

L. Stephens, J. D. Padmos, M. Narouz, A. Al-Rashed, C.-H. Li, N. Payne, M.T. Zamora, C.M. Crudden*, J. Mauzeroll*, J.H. Horton*, “The Structural and Electrochemical Effects of N-Heterocyclic Carbene Monolayers on Magnesium.” Journal of the Electrochemical Society, 2018, 165(13) G139-G145.

R.W.Y. Man, C.-H. Li, M.W.A. MacLean, O.V. Zenkina, M.T. Zamora, L.N. Saunders, A. Rousina-Webb, M. Nambo, C.M. Crudden, “Ultra Stable Gold Nanoparticles Modified by Bidentate N-Heterocyclic Carbene Ligands,” Journal of the American Chemical Society, 2018, 140 (5), 1576-1579. 

Z. T. Ariki, Y. Maekawa, M. Nambo, C. M. Crudden, “Preparation of Quaternary Centers via Nickel-Catalyzed Suzuki-Miyaura Cross-Coupling of Tertiary Sulfones,” Journal of the American Chemical Society, 2018, 140 (1), 78-81. 

J.J. Clarke, P. Eisenberger, S.S. Piotrkowski and C.M. Crudden. “Azaborines: Synthesis and Use in the Generation of Stabilized boron-substituted carbocations,” Dalton Transactions, 2018, 47, 1791-1795. 


Z. Li, M.R. Narouz, K. Munro, B. Hao, C.M. Crudden, J.H. Horton, H. Hao “Carboxymethylated Dextran-Modified N-Heterocyclic Carbene Self-Assembled Monolayers on Gold for Use in Surface Plasmon Resonance Biosensing.” ACS Applied Materials & Interfaces, 2017, 9, (45), 39223-39234.

C.R. Larrea, C.J. Baddeley*, M.R. Narouz, N.J. Mosey, J.H. Horton, C.M. Crudden, “N-Heterocyclic Carbene Self-assembled Monolayers on Copper and Gold: Dramatic Effect of Wingtip Groups on Binding, Orientation and Assembly,” ChemPhysChem.2017, 18, 24, 3536-3539.

J. P. G. Rygus, C. M. C. Crudden, “Enantiospecific and Iterative Suzuki-Miyaura Cross-Couplings,” Journal of the American Chemical Society Spotlights, 2017, 139 (50), 18123. 

M.R. Narouz, C.-H. Li, A. Nazemi, C.M. Crudden, “Amphiphilic N-Heterocyclic Carbene-Stabilized Gold Nanoparticles and their Self-Assembly in Polar Solvents,” Langmuir, 201733 (50), 14211-14219. 

Z. Li, K. Munro, I. Ebralize, J.D. Padmos, M.R. Narouz, J.D. Padmos, H. Hao, C.M. Crudden. J.H. Horton, “N-Heterocyclic Carbene Self-Assembled Monolayers on Gold as Surface Plasmon Resonance Biosensors,” Langmuir, 2017, 33 (49), 13936-13944.

M. Nambo, J. Yim, K. Fowler, C.M. Crudden, “Synthesis of Tetraarylmethanes by the Triflic Acid-Promoted Formal Cross Dehydrogenative Coupling of Triarylmethanes with Arenes,” Synlett, 2017, 28 (20), 2936-2940.

M. Nambo, J. Yim, C.M. Crudden, “Pd-Catalyzed Desulfonative Cross-Coupling of Benzylic Sulfone Derivatives with 1,3-Oxazole,” Organic Letters, 2017, 19(14) 3715-3718.

K. Salorinne, R.W.Y. Man, C-H. Li, M. Taki, M. Nambo, C.M. Crudden, “Water Soluble N-Heterocyclic Carbene-Protected Gold Nanoparticles: Synthesis, Stability and Optical Properties,” Angewandte Chem. Intl. Ed., 2017, 56 (22), 6198-6202. 

P. Eisenberger, C. M. Crudden, “Borocation Catalysis,” Dalton Trans., 2017, 46, 4874-4887. 


M. Nambo. E.C. Keske, J.P.G. Rygus, J.C.-H. Yim, C.M.Crudden, “Development of Versatile Sulfone Electrophiles for Suzuki–Miyaura Cross-Coupling Reactions,” ACS Catalysis, 2016, 7 (2), 1108–1112.

L.M. Reid & C.M. Crudden, “Installing Stable Molecular Chirality within the Walls of Periodic Mesoporous Organosilicas via Self-Assembly,” Chem. Mater., 201628(21), 7605-7612.

C.M. Crudden*, J.H. Horton*, M.R. Narouz, Z. Li, C.A. Smith, K. Munro, C.J. Baddeley, C.R. Larrea, B. Drevniok, B. Thanabalasingam, A.B. McLean, O.V. Zenkina, I.I. Ebralidze, Z. She, H.-B. Kraatz, N.J. Mosey, L.N. Saunders, A. Yagi, “Simple direct formation of self-assembled N-heterocyclic carbene monolayers on gold and their application in biosensing”, Nature Communications 2016, 7, 12654.

J. Lam, B.A.R. Günther, J.M. Farrell, P. Eisenberger,* B.P. Bestvater, P.D. Newman, R.L. Melen*, C.M. Crudden*, D.W. Stephan* “Chiral Carbene–Borane Adducts: Precursors for Borenium Catalysts for Asymmetric FLP Hydrogenations”, Dalton Transactions201645, 15303-15316.

L.M. Reid, G. Wu, C.M. Crudden*, “Accessible bidentate diol functionality within highly ordered composite periodic mesoporous organosilicas”, New Journal of Chemistry, 2016, 40, 6487-6497. 

M. Nambo, Z.T. Ariki, D. Canseco-Gonzalez, D.D. Beattie, and C.M. Crudden, “Arylative Desulfonation of Diarylmethyl Phenyl Sulfone with Arenes Catalyzed by Scandium Triflate”. Organic Letters, 201618 (10), 2339–2342.

I. R. Nemitz, K. McEleney, C. M. Crudden, R. P. Lemieux, R. G. Petschek, C. Rosenblatt*, “Chiral Periodic Mesoporous Organosilica in a Smectic-A Liquid Crystal: Source of the Electrooptic Response”. Liquid Crystals, 2016, 43, 497-504.

C.M. Crudden, C. Ziebenhaus, J. P. G. Rygus, K. Ghozati, P. J. Unsworth, M. Nambo, S. Voth, M. Hutchinson, V. S. Laberge, Y. Maekawa, D. Imao “Iterative protecting group-free cross-coupling leading to chiral multiply arylated structures.” Nature Communications2016, 7, 11065.


M. Nambo, C.M. Crudden, “Recent Advances in the Synthesis of Triarylmethanes by Transition Metal Catalysis” ACS Catalysis, 2015, 5, (8), 4734–4742.

P. Eisenberger, B. P. Bestvater, E. C. Keske, C.M. Crudden*, “Hydrogenations at Room Temperature and Atmospheric Pressure with Mesoionic Carbene-Stabilized Borenium Catalysts” Angewandte Chemie International Edition, 2015, 54 (8), 2467-2471.

M. Nambo, M. Yar, J.D. Smith, C.M. Crudden, “The Concise Synthesis of Unsymmetric Triarylacetonitriles via Pd-Catalyzed Sequential Arylation: A New Synthetic Approach to Tri-and Tetraarylmethanes”, Org. Lett.2015, 17 (1), 50–53.

J.D. Webb, T. Seki, J.F. Goldston, M. Pruski, C.M. Crudden, “Highly Selective Functionalization of the Mesopores of SBA-15” Micro. Meso. Mater., 2015, 203, 123–131.

M.W.A. MacLean, L.M. Reid, X. Wu, C.M. Crudden, “Chirality in Ordered Porous Organosilica Hybrid Materials”, Chem. Asian J. (invited)2015, 10 (1), 70-82.